Symbol
Name
ID

Thsd4
thrombospondin, type I, domain containing 4
MGI:2672033

Phenotype annotations related to cardiovascular system

Darker colors indicate more annotations

Human Phenotypes

Subarachnoid hemorrhage

Bruising susceptibility

Bicuspid aortic valve

Cardiomegaly

Ascending aortic dissection

Aortic aneurysm

Abdominal aortic aneurysm

Thoracic aortic aneurysm

Aortic root aneurysm

Ascending tubular aorta aneurysm

Descending thoracic aorta aneurysm

Aortic dissection

Descending aortic dissection

Aortic rupture

Mucoid extracellular matrix accumulation

Patent ductus arteriosus

Carotid artery dilatation

Carotid artery stenosis

Anterior cerebral artery stenosis

Middle cerebral artery stenosis

Posterior cerebral artery stenosis

Dilatation of the cerebral artery

Moyamoya phenomenon

Coronary artery aneurysm

Coronary artery atherosclerosis

Premature coronary artery atherosclerosis

Coronary artery dissection

Peripheral arterial stenosis

Cystic medial necrosis

Stroke

Ischemic stroke

Transient ischemic attack

Abnormal left ventricular function

Aortic regurgitation

Hypertension

Hypovolemia

Cutis marmorata

Livedo reticularis

Disease(s) Associated with THSD4

thoracic aortic aneurysm

Mouse Phenotypes		abnormal aorta morphology	abnormal aorta smooth muscle morphology	descending aorta dilation	aortic arch dilation	abnormal aortic sinus morphology	dilated ascending aorta	dilated aorta
Availability	Mouse Genotype
	Thsd4^tm1.2Lysa/Thsd4⁺

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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